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      Bcl-2 Mouse mAb
      EM1041
      規格: 價格:
      50 μl ¥1280.00
      100 μl ¥1980.00

      Overview

      Product name: Bcl-2 Mouse mAb
      Alternative Names: B-Cell Leukemia/Lymphoma 2 ;B-Cell CLL/Lymphoma 2
      Source: Mouse
      Applications: WB, IHC, IF
      Reactivity: Human, Rat, Mouse
      Dilutions: WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
      Immunogen: Synthetic Peptide
      Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
      Clonality: Monoclonal
      Isotype: IgG1
      Concentration: 1mg/ml
      Observed Band: 26kDa
      GeneID(Human): 596
      Human Swiss-Prot No: P10415
      Cellular localization: Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane
      Background: BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
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