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      CD45 Mouse mAb
      EM1046
      規格: 價格:
      50 μl ¥1280.00
      100 μl ¥1980.00

      Overview

      Product name: CD45 Mouse mAb
      Alternative Names: B220, CD45R, GP180, L CA, LCA, Leukocyte common antigen, LY5, PTPRC, RPTPC, T200
      Source: Mouse
      Applications: WB
      Reactivity: Human
      Dilutions: WB 1:2,000 IHC 1:200
      Immunogen: Synthetic Peptide
      Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
      Clonality: Monoclonal
      Isotype: IgG1
      Concentration: 1mg/ml
      Observed Band: 147kDa
      GeneID(Human): 5788
      Human Swiss-Prot No: P08575
      Cellular localization: Membrane
      Background: CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45.
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