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      CK19 Mouse mAb
      EM1051
      規格: 價格:
      50 μl ¥1280.00
      100 μl ¥1980.00

      Overview

      Product name: CK19 Mouse mAb
      Alternative Names: Cytokeratin 19, K19, K1CS, keratin 19, KRT19
      Source: Mouse
      Applications: IHC
      Reactivity: Human, Rat, Mouse
      Dilutions: IHC 1:200
      Immunogen: Synthetic Peptide
      Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
      Clonality: Monoclonal
      Isotype: IgG1
      Concentration: 1mg/ml
      Observed Band: 44kDa
      GeneID(Human): 3880
      Human Swiss-Prot No: P08727
      Cellular localization: Cytoskeleton,Cytosol
      Background: This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
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